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APPP is a drug that acts as a potent agonist for the cannabinoid receptors, with Ki values of 0.9 nM at CB1 and 23.2 nM at CB2 and EC50 values of 1.8 nM at CB1 and 3.2 nM at CB2. It was originally developed by Pfizer in 2009 as an analgesic medication but was never pursued for human use. In 2012, it was discovered as an ingredient in synthetic cannabinoid blends in Japan, along with a related compound AB-PINACA, which had not previously been reported.


How to use the Powder?

APPP for sale in the highest quality powder form. Buy  in the quantities  10gr, 50gr, and 500gr. Ensure to store the APPP powder in a dry and cool place for maximum shelf-life. Store in a dry and cool place for maximum shelf-life. When handling research chemicals ensure to always take the proper precautions in the laboratory like wiping down surfaces and wearing gloves, a mask & protective clothing.


Definition of APPP

 A novel synthetic cannabinoid compound. Members of this group produce cannabis-like effects when administered. Commonly smoked or vaporized to achieve rapid effects and offset. APPP is orally active when dissolved in a lipid, which can increase the duration significantly. Like other cannabinoids, it is insoluble in water but dissolves in ethanol and lipids.


Due to the lack of studies and brief research history regarding the substance, all discussions of ab-fubinaca are purely based on its structure and subjective effect similarities to other arylcyclohexylamine dissociatives such as DCK and ketamine. Therefore, strongly advised to use harm reduction practices using this substance.


Where to buy APPP

APPP can be purchased here on the synthetick2cannabinoids website. We sell premium quality APPP, typically in powder. However, we often have other substance forms available, so feel free to contact us to see if we have your preferred substance form in stock. You must be at least 18 years old to buy APPP from us.


Massive overdose of APPP

On August 15th, 2018, 70 people within the city of New Haven, Connecticut started overdosing near Yale University campus. By the end of the week, the total number of overdosed had risen to over 100 people needing transport to local emergency rooms. Almost all of the overdoses occurred on the New Haven Green, a large downtown park. Heavily traveled and very popular with the homeless population. No deaths associated with these overdoses; however, several victims are in critical or life-threatening condition


Safe shipping APPP* to Canada, Italy, Brazil, Switzerland, Australia, New zealand, France, Germany, Japan, Russia, Mexico, Egypt, Turkey, Spain, Argentina, Poland, Morocco, Saudi Arabia, Romania, Kazakhstan, Netherlands, Belgium, Greece, Tunisia, Czech Republic, Dominican Republic, Portugal, Hungary, Israel, Bulgaria, Finland, Denmark, Slovakia, Norway, Ireland, Croatia, Armenia, Lithuania, Slovenia, Latvia, Estonia and many other countries.

Other important products: 2 fdck, ketamine psychedelic, 2cb yellow pills, cannabinoid c liquid, U48800, MDPHP, AB-FUBINACA, 5-MEO-DMT, 5FADB, ADBB.

Additional information


10g, 50g, 100g, 500g, 1000g


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